Please use this identifier to cite or link to this item:
http://hdl.handle.net/11452/33016
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chen, Chung-Hwan | - |
dc.contributor.author | Elsalmawy, Abdulaziz H. | - |
dc.contributor.author | Ish-Shalom, Sophia | - |
dc.contributor.author | Lim, Seung-Jae | - |
dc.contributor.author | Ai-Ali, Nadia S. | - |
dc.contributor.author | Cunha-Borges, Joao L. | - |
dc.contributor.author | Yang, Huilin | - |
dc.contributor.author | Casas, Noemi | - |
dc.contributor.author | Altan, Lale | - |
dc.contributor.author | Moll, Thomas | - |
dc.contributor.author | Gurbuz, Sirel | - |
dc.contributor.author | Brnabic, Alan J. M. | - |
dc.contributor.author | Burge, Russel T. | - |
dc.contributor.author | Marin, Fernando | - |
dc.date.accessioned | 2023-06-13T06:07:12Z | - |
dc.date.available | 2023-06-13T06:07:12Z | - |
dc.date.issued | 2019-06-03 | - |
dc.identifier.citation | Chen, C.H. vd. (2019). ''Study description and baseline characteristics of the population enrolled in a multinational, observational study of teriparatide in postmenopausal women with osteoporosis: the Asia and Latin America Fracture Observational Study (ALAFOS)''. Current Medical Research and Opinion, 35(6), 1041-1049. | en_US |
dc.identifier.issn | 0300-7995 | - |
dc.identifier.issn | 1473-4877 | - |
dc.identifier.uri | https://doi.org/10.1080/03007995.2018.1552576 | - |
dc.identifier.uri | https://www.tandfonline.com/doi/full/10.1080/03007995.2018.1552576 | - |
dc.identifier.uri | http://hdl.handle.net/11452/33016 | - |
dc.description.abstract | Objective: To describe the study design and baseline patient characteristics of the Asia and Latin America Fracture Observational Study (ALAFOS) to better understand the profile of patients receiving teriparatide during the course of routine clinical practice in Asia, Latin America, the Middle East and Russia. Methods: Prospective, observational, non-interventional study in postmenopausal women with osteoporosis who are prescribed teriparatide for up to 24 months, according to local medical standards, with a 12 month post-treatment follow-up. Measures: Demographics, risk factors for osteoporosis and fractures, history of fracture, prior osteoporosis medications, comorbidities, physical function, back pain and quality of life (QoL). Results: In total 3031 postmenopausal women (mean age 72.5 years) recruited at 152 sites in 20 countries were analyzed; 62.9% had a history of fragility fracture after age 40 (33.0% of patients with spinal, 14.2% with hip fractures). The mean (SD) bone mineral density T-scores at baseline were -3.06 (1.40) and -2.60 (1.05) at the lumbar spine and femoral neck, respectively. At entry, 43.7% of patients were naive to prior osteoporosis treatments; 40.5% of patients reported >= 1 fall in the past year. The median (Q1; Q3) EuroQoL Visual Analog Scale (EQ-VAS) for perceived overall health status was 60 (50; 80). The mean (SD) worst back pain Numeric Rating Scale in the last 24 hours was 4.6 (3.3). Conclusions: Our data indicates that patients who were prescribed teriparatide in the ALAFOS participant countries had severe osteoporosis, high prevalence of fractures, disabling back pain and poor QoL. The frequency of patients receiving prior osteoporosis medications was lower than in previous observational studies conducted in other locations. | en_US |
dc.description.sponsorship | Eli Lilly B3D-MC-B026 | en_US |
dc.language.iso | en | en_US |
dc.publisher | Taylor | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | General & internal medicine | en_US |
dc.subject | Research & experimental medicine | en_US |
dc.subject | Fractures | en_US |
dc.subject | Observational study | en_US |
dc.subject | Osteoporosis | en_US |
dc.subject | Teriparatide | en_US |
dc.subject | Questionnaire-physical function | en_US |
dc.subject | Parathyroıd-hormone 1-34 | en_US |
dc.subject | Quality-of-life | en_US |
dc.subject | Opaq-pf | en_US |
dc.subject | Prevention | en_US |
dc.subject | Guidelines | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Aged, 80 and over | en_US |
dc.subject.mesh | Bone Density | en_US |
dc.subject.mesh | Bone Density Conservation Agents | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Fractures, Bone | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Osteoporosis, Postmenopausal | en_US |
dc.subject.mesh | Postmenopause | en_US |
dc.subject.mesh | Prospective Studies | en_US |
dc.subject.mesh | Quality of Life | en_US |
dc.subject.mesh | Teriparatide | en_US |
dc.title | Study description and baseline characteristics of the population enrolled in a multinational, observational study of teriparatide in postmenopausal women with osteoporosis: the Asia and Latin America Fracture Observational Study (ALAFOS) | en_US |
dc.type | Article | en_US |
dc.identifier.wos | 000466409100012 | tr_TR |
dc.identifier.scopus | 2-s2.0-85059678240 | tr_TR |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.contributor.department | Bursa Uludağ Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri/Fizik Tedavi ve Rehabilitasyon Bölümü. | tr_TR |
dc.identifier.startpage | 1041 | tr_TR |
dc.identifier.endpage | 1049 | tr_TR |
dc.identifier.volume | 35 | tr_TR |
dc.identifier.issue | 6 | tr_TR |
dc.relation.journal | Current Medical Research and Opinion | en_US |
dc.contributor.buuauthor | Altan, Lale | - |
dc.contributor.researcherid | AAH-1652-2021 | tr_TR |
dc.relation.collaboration | Yurt dışı | tr_TR |
dc.relation.collaboration | Sanayi | tr_TR |
dc.identifier.pubmed | 30474449 | tr_TR |
dc.subject.wos | Medicine, general & internal | en_US |
dc.subject.wos | Medicine, research & experimental | en_US |
dc.indexed.wos | SCIE | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.pubmed | PubMed | en_US |
dc.wos.quartile | Q2 (Medicine, general & internal) | en_US |
dc.wos.quartile | Q3 (Medicine, research & experimental) | en_US |
dc.contributor.scopusid | 6603281363 | tr_TR |
dc.subject.scopus | Parathyroid Hormone[1-34]; Osteoporosis; AMG 785 | en_US |
dc.subject.emtree | Nonsteroid antiinflammatory agent | en_US |
dc.subject.emtree | Opiate | en_US |
dc.subject.emtree | Paracetamol | en_US |
dc.subject.emtree | Parathyroid hormone[1-34] | en_US |
dc.subject.emtree | Bone density conservation agent | en_US |
dc.subject.emtree | Adult | en_US |
dc.subject.emtree | Anxiety disorder | en_US |
dc.subject.emtree | Argentina | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Asia | en_US |
dc.subject.emtree | Australia | en_US |
dc.subject.emtree | Backache | en_US |
dc.subject.emtree | Bone density | en_US |
dc.subject.emtree | Brazil | en_US |
dc.subject.emtree | Calcaneus | en_US |
dc.subject.emtree | China | en_US |
dc.subject.emtree | Clavicle | en_US |
dc.subject.emtree | Clinical practice | en_US |
dc.subject.emtree | Colombia | en_US |
dc.subject.emtree | Comorbidity | en_US |
dc.subject.emtree | Depression | en_US |
dc.subject.emtree | Disease course | en_US |
dc.subject.emtree | Distal femur | en_US |
dc.subject.emtree | European Quality of Life 5 Dimensions 5 Level questionnaire | en_US |
dc.subject.emtree | European Quality of Life 5 Dimensions questionnaire | en_US |
dc.subject.emtree | European Quality of Life 5 Dimensions Visual Analogue Scale | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Fibula | en_US |
dc.subject.emtree | Femur diaphysis | en_US |
dc.subject.emtree | Femoral neck | en_US |
dc.subject.emtree | Follow up | en_US |
dc.subject.emtree | Lebanon | en_US |
dc.subject.emtree | Kuwait | en_US |
dc.subject.emtree | Israel | en_US |
dc.subject.emtree | Human | en_US |
dc.subject.emtree | Hong Kong | en_US |
dc.subject.emtree | Hip fracture | en_US |
dc.subject.emtree | Hip | en_US |
dc.subject.emtree | Fragility fracture | en_US |
dc.subject.emtree | Major clinical study | en_US |
dc.subject.emtree | Multicenter study | en_US |
dc.subject.emtree | Middle East | en_US |
dc.subject.emtree | Mexico | en_US |
dc.subject.emtree | Metatarsal bone | en_US |
dc.subject.emtree | Menopause | en_US |
dc.subject.emtree | Medical history | en_US |
dc.subject.emtree | Malaysia | en_US |
dc.subject.emtree | Numeric rating scale | en_US |
dc.subject.emtree | Observational study | en_US |
dc.subject.emtree | Physical performance | en_US |
dc.subject.emtree | Postmenopause | en_US |
dc.subject.emtree | Postmenopause osteoporosis | en_US |
dc.subject.emtree | Prescription | en_US |
dc.subject.emtree | Prospective study | en_US |
dc.subject.emtree | Quality of life | en_US |
dc.subject.emtree | Radius | en_US |
dc.subject.emtree | Reimbursement | en_US |
dc.subject.emtree | Rib | en_US |
dc.subject.emtree | Risk factor | en_US |
dc.subject.emtree | Russian Federation | en_US |
dc.subject.emtree | Sacrum | en_US |
dc.subject.emtree | Saudi Arabia | en_US |
dc.subject.emtree | Scapula | en_US |
dc.subject.emtree | Singapore | en_US |
dc.subject.emtree | South and Central America | en_US |
dc.subject.emtree | South Korea | en_US |
dc.subject.emtree | Spine fracture | en_US |
dc.subject.emtree | Taiwan | en_US |
dc.subject.emtree | Tarsal bone | en_US |
dc.subject.emtree | Thailand | en_US |
dc.subject.emtree | Tibia | en_US |
dc.subject.emtree | Turkey (republic) | en_US |
dc.subject.emtree | Visual analog scale | en_US |
dc.subject.emtree | Wrist | en_US |
dc.subject.emtree | Aged | en_US |
dc.subject.emtree | Clinical trial | en_US |
dc.subject.emtree | Fracture | en_US |
dc.subject.emtree | Middle aged | en_US |
dc.subject.emtree | Postmenopause osteoporosis | en_US |
dc.subject.emtree | Psychology | en_US |
dc.subject.emtree | Very elderly | en_US |
Appears in Collections: | Scopus Web of Science |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.