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http://hdl.handle.net/11452/33106
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Dublin Core Alanı | Değer | Dil |
---|---|---|
dc.contributor.author | Sebik, Oğuz | - |
dc.contributor.author | Çelebi, Gürbüz | - |
dc.date.accessioned | 2023-06-22T07:07:05Z | - |
dc.date.available | 2023-06-22T07:07:05Z | - |
dc.date.issued | 2013-07 | - |
dc.identifier.citation | Sağdilek, E. vd. (2013). “Does the magnetic field of a magnetic stirrer in an optical aggregometer affect concurrent platelet aggregation?”. Bioelectromagnetics, 34(5), 349-357. | en_US |
dc.identifier.issn | 0197-8462 | - |
dc.identifier.uri | https://doi.org/10.1002/bem.21785 | - |
dc.identifier.uri | https://onlinelibrary.wiley.com/doi/10.1002/bem.21785 | - |
dc.identifier.uri | http://hdl.handle.net/11452/33106 | - |
dc.description.abstract | Platelets are subjected to extremely low frequency electromagnetic fields during standard aggregometry measurements owing to the use of a magnetic stir bar in the instrument. This study evaluates the effects of this magnetic field exposure on platelet aggregation by comparing the results obtained in a modified aggregometer. Blood samples from healthy volunteers were anticoagulated using citrate or heparin. Platelet-rich plasma (PRP) samples were prepared. A mechanical stirring device was attached to the aggregometer instead of the magnetic stir bar system. The PRP samples were stirred using a stirring rod tip that did not produce any magnetic fields in one channel of the aggregometer; in the other channel, a stirring rod carrying a small magnet at its tip was used. As a result, a magnetic field in the extremely low frequency range and in the amplitude range of 1.9-65mT was applied to the platelets assigned to the channel where the magnetic stirring rod tip was used. Aggregation was induced using adenosine diphosphate (ADP), collagen, or epinephrine. The slopes, maximum aggregation values, and areas under the aggregation curves were compared between the magnetic and neutral stirring rod tip groups. For samples stirred with the magnetic stirring rod tip, a significant decrease was observed in 12 of the 14 parameters evaluated for aggregations induced with ADP or collagen compared to the neutral stirring rod tip, regardless of the method used for anticoagulation. This observation indicates that the magnetic stir bars used in standard aggregometry may significantly alter aggregation parameters and platelets may be possible targets of electromagnetic fields. | en_US |
dc.description.sponsorship | Ege Üniversitesi (2008-TIP-013) | tr_TR |
dc.language.iso | en | en_US |
dc.publisher | Wiley | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Life sciences & biomedicine - other topics | en_US |
dc.subject | Biophysics | en_US |
dc.subject | Platelets | en_US |
dc.subject | Modified aggregometry | en_US |
dc.subject | Stir bar | en_US |
dc.subject | Frequency electromagnetic-fields | en_US |
dc.subject | Adenylate kinase-activity | en_US |
dc.subject | Rod outer segment | en_US |
dc.subject | In-vitro | en_US |
dc.subject | Blood-platelets | en_US |
dc.subject | Cells | en_US |
dc.subject | Metabolism | en_US |
dc.subject | Exposure | en_US |
dc.subject | Collagen | en_US |
dc.subject | Electromagnetic fields | en_US |
dc.subject | Magnetic field effects | en_US |
dc.subject | Plasma (human) | en_US |
dc.subject | Adenosine diphosphate | en_US |
dc.subject | Elf-emf | en_US |
dc.subject | Magnetic stir bars | en_US |
dc.subject | Magnetic stirring | en_US |
dc.subject | Magnetic-field | en_US |
dc.subject | Modified aggregometry | en_US |
dc.subject | Plasma samples | en_US |
dc.subject | Platelet aggregation | en_US |
dc.subject | Platelet rich plasma | en_US |
dc.subject | Stir bar | en_US |
dc.subject | Platelets | en_US |
dc.subject.mesh | Adenosine diphosphate | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Anticoagulants | en_US |
dc.subject.mesh | Area under curve | en_US |
dc.subject.mesh | Blood specimen collection | en_US |
dc.subject.mesh | Citric acid | en_US |
dc.subject.mesh | Collagen | en_US |
dc.subject.mesh | Electromagnetic fields | en_US |
dc.subject.mesh | Epinephrine | en_US |
dc.subject.mesh | Equipment design | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Heparin | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Magnetic fields | en_US |
dc.subject.mesh | Magnets | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle aged | en_US |
dc.subject.mesh | Optical Devices | en_US |
dc.subject.mesh | Platelet aggregation | en_US |
dc.subject.mesh | Platelet function tests | en_US |
dc.subject.mesh | Platelet-rich plasma | en_US |
dc.subject.mesh | Spectrophotometry | en_US |
dc.subject.mesh | Young adult | en_US |
dc.title | Does the magnetic field of a magnetic stirrer in an optical aggregometer affect concurrent platelet aggregation? | en_US |
dc.type | Article | en_US |
dc.identifier.wos | 000319965000002 | tr_TR |
dc.identifier.scopus | 2-s2.0-84878734407 | tr_TR |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Biyofizik Anabilim Dalı. | tr_TR |
dc.relation.bap | T-2008/47 | tr_TR |
dc.identifier.startpage | 349 | tr_TR |
dc.identifier.endpage | 357 | tr_TR |
dc.identifier.volume | 34 | tr_TR |
dc.identifier.issue | 5 | tr_TR |
dc.relation.journal | Bioelectromagnetics | en_US |
dc.contributor.buuauthor | Sağdilek, Engin | - |
dc.contributor.researcherid | AAH-4397-2021 | tr_TR |
dc.relation.collaboration | Yurt içi | tr_TR |
dc.identifier.pubmed | 23436227 | tr_TR |
dc.subject.wos | Biology | en_US |
dc.subject.wos | Biophysics | en_US |
dc.indexed.wos | SCIE | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.pubmed | PubMed | en_US |
dc.wos.quartile | Q2 (Biology) | en_US |
dc.wos.quartile | Q3 (Biophysics) | en_US |
dc.contributor.scopusid | 16835756600 | tr_TR |
dc.subject.scopus | Extremely Low Frequencies; Salmonella Hadar; Microorganisms | en_US |
dc.subject.emtree | Adenosine diphosphate | en_US |
dc.subject.emtree | Adrenalin | en_US |
dc.subject.emtree | Anticoagulant agent | en_US |
dc.subject.emtree | Citric acid | en_US |
dc.subject.emtree | Collagen | en_US |
dc.subject.emtree | Heparin | en_US |
dc.subject.emtree | Adult | en_US |
dc.subject.emtree | Area under the curve | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Blood clotting parameters | en_US |
dc.subject.emtree | Blood sampling | en_US |
dc.subject.emtree | Comparative study | en_US |
dc.subject.emtree | Controlled clinical trial | en_US |
dc.subject.emtree | Controlled study | en_US |
dc.subject.emtree | Drug effect | en_US |
dc.subject.emtree | Electromagnetic field | en_US |
dc.subject.emtree | Equipment | en_US |
dc.subject.emtree | Equipment design | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Human | en_US |
dc.subject.emtree | Magnet | en_US |
dc.subject.emtree | Magnetic field | en_US |
dc.subject.emtree | Male | en_US |
dc.subject.emtree | Methodology | en_US |
dc.subject.emtree | Middle aged | en_US |
dc.subject.emtree | Optical instrumentation | en_US |
dc.subject.emtree | Radiation exposure | en_US |
dc.subject.emtree | Randomized controlled trial | en_US |
dc.subject.emtree | Spectrophotometry | en_US |
dc.subject.emtree | Thrombocyte aggregation | en_US |
dc.subject.emtree | Thrombocyte rich plasma | en_US |
Koleksiyonlarda Görünür: | Scopus Web of Science |
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