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Başlık: Detrimental effects of endometriosis on oocyte morphology in intracytoplasmic sperm injection cycles: A retrospective cohort study
Yazarlar: Uludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Histoloji ve Embriyoloji Anabilim Dalı.
0000-0002-0338-8368
0000-0001-5637-2741
Kasapoğlu, Işıl
Kuşpınar, Gökhan
Sarıbal, Seda
Türk, Pınar
Avcı, Berrin
Uncu, Gürkan
AAH-5119-2021
AAT-3479-2021
ABE-6685-2020
HTQ-5866-2023
55800494800
57200388474
56741562000
57200393116
6603017388
6603716169
Anahtar kelimeler: Endocrinology & metabolism
Obstetrics & gynecology
Endometriosis
Oocyte morphology
Infertility
Intracytoplasmic sperm injection
In-vitro fertilization
Recombinant human fsh
Infertile women
Progesterone elevation
Oxidative stress
Ovarian reserve
Pregnancy rates
Embryo-transfer
Quality
Outcomes
Yayın Tarihi: 9-Eki-2017
Yayıncı: Taylor & Francis
Atıf: Kasapoğlu, I. vd. (2018). ''Detrimental effects of endometriosis on oocyte morphology in intracytoplasmic sperm injection cycles: A retrospective cohort study''. Gynecological Endocrinology, 34(3), 206-211.
Özet: While an association can be addressed among endometriosis and subfertility, the causal relationship has not been elucidated yet. Impaired oocyte quality in endometriosis patients has been accused for the unsuccessful outcomes of assisted reproductive techniques. There are limited studies in literature evaluated association between endometriosis and oocyte morphology. We conducted this retrospective study to evaluate whether morphological abnormalities of oocytes are more common in women with endometriosis than women with diagnosis of male factor infertility as a source of healthy oocytes. Totally 1568 oocytes, 775 (49.4%) in endometriosis groups and 793 (50.6%) in control group were evaluated for morphological parameters before ICSI cycles. Abnormal oocyte morphology was detected in 352 (22.4%) of 1568 oocytes. Of the abnormal oocytes, 208 (59.1%) were in endometriosis group and 144 (40.9%) in control group (p < .001). The following dysmorphisms were significantly higher in oocytes retrieved from endometriosis group: dark cytoplasm; dark, large or thin zona pellucida; and flat or fragmented polar body (p < .05 for all). When morphological parameters for oocytes of endometriosis patients evaluated, the oocyte defects has increased significantly in endometriosis patients. These findings are thought to be useful to clarify the subfertility in endometriosis patient, which needs to be confirmed with further studies.
URI: https://doi.org/10.1080/09513590.2017.1391203
https://www.tandfonline.com/doi/full/10.1080/09513590.2017.1391203
http://hdl.handle.net/11452/34051
ISSN: 0951-3590
1473-0766
Koleksiyonlarda Görünür:Scopus
Web of Science

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