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Başlık: Anastomotic leaks at the pancreaticojejunostomy following pancreaticoduodenectomy in patients with pancreatic head adenocarcinoma increases the local recurrence rate
Yazarlar: Uludağ Üniversitesi/Tıp Fakültesi/Cerrahi Anabilim Dalı.
0000-0002-9562-4195
0000-0002-9541-5035
0000-0002-9541-5035
Dündar, Halit Ziya
Taşar, Pınar
Işık, Özgen
Kaya, Ekrem
AAG-7319-2021
ABH-2238-2021
P-5779-2019
AAW-9602-2020
55453773300
57208702845
36600543700
7004568109
Anahtar kelimeler: Surgery
Leakage
Pancreatic cancer
Recurrence
Hospital volume
Cuctal adenocarcinoma
Curative resection
Colorectal-cancer
Survival
Complications
Fistula
Impact
Experience
Management
Yayın Tarihi: 2018
Yayıncı: Edizioni Luigi Pozzi
Atıf: Dündar, H. Z. vd. (2018). ''Anastomotic leaks at the pancreaticojejunostomy following pancreaticoduodenectomy in patients with pancreatic head adenocarcinoma increases the local recurrence rate''. Annali italiani di chirurgia, 89(4), 315-319.
Özet: INTRODUCTION: In contrast to colorectal cancer patients, the effect of anastomosis leakage following pancreatic adenocarcinoma surgery on survival and recurrence rate is not clear. The present study aimed to determine the effect of pancreaticojejunostomy (PJ) anastomosis leakage, especially on the local recurrence rate and time of recurrence, in patients that underwent pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma. MATERIALS AND METHODS: This retrospective study included 64 pancreatic adenocarcinoma patients that underwent PD between January 2007 and August 2015. PJ anastomosis leakage was evaluated based on International Study Group on Pancreatic Fistula criteria. The effects of PJ anastomosis leakage on local recurrence, disease-free survival, and overall survival were assessed. RESULTS: Among the patients, 44 were male and 20 were female, and median age was 61(39-84) years. In all, 11 patients developed PJ leakage. Local recurrence occurred in 5 (45,4%) of the patients that developed PJ leakage, versus in 4 (7,5%) of the patients without leakage (p=0.02). Local recurrence developed earlier in those with leakage than in those without (p=0,013). In contrast, there weren't any significant differences in disease-free survival, or overall survival. CONCLUSION: PJ leakage seems to be associated with more frequent and earlier local recurrence while it did not influence survival.
URI: https://www.annaliitalianidichirurgia.it/wp-content/uploads/2018/10/05_2882blocco.pdf
http://hdl.handle.net/11452/34102
ISSN: 0003-469X
2239-253X
Koleksiyonlarda Görünür:Scopus
Web of Science

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