Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/34238
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dc.contributor.authorYıldız, Demet-
dc.contributor.authorTufan, Fatih-
dc.date.accessioned2023-10-06T08:16:13Z-
dc.date.available2023-10-06T08:16:13Z-
dc.date.issued2015-
dc.identifier.citationYıldız, D. vd. (2015). "Impaired cognitive performance and hippocampal atrophy in Parkinson disease". Turkish Journal of Medical Sciences, 45(5), Special Issue, 1173-1177.tr_TR
dc.identifier.issn1300-0144-
dc.identifier.urihttps://doi.org/10.3906/sag-1408-68-
dc.identifier.urihttps://journals.tubitak.gov.tr/medical/vol45/iss5/28/-
dc.identifier.urihttp://hdl.handle.net/11452/34238-
dc.description.abstractBackground/aim: Dementia is common in Parkinson disease (PD). Since magnetic resonance imaging has been used, hippocampal atrophy has been shown in PD patients with or without dementia. In this study we sought the correlation of cognitive decline with bilateral hippocampal volume in PD patients. Materials and methods: Thirty-three patients with diagnosis of idiopathic PD and 16 healthy subjects were included in this study. PD patients were divided into two groups as normal cognitive function and mild cognitive impairment (MCI). The Mini-Mental State Examination and detailed cognitive assessment tests were performed for all patients for cognitive analyses. Depression was excluded by the Geriatric Depression Scale. Results: The mean onset age of disease was 55 years for PD patients without dementia and 59 for PD patients with MCI. According to the Hoehn-Yahr scales, 24% of patients had grade 1, 58% had grade 2, and 18% had grade 3 disease. Right and left hippocampal volumes decreased along with cognitive test scores in PD patients. Increased right hippocampal volume was correlated with forward number test in the MCI-PD group. Conclusion: These findings suggest that memory deficit is associated with hippocampal atrophy in PD patients.en_US
dc.language.isoenen_US
dc.publisherTÜBİTAKtr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAtıf Gayri Ticari Türetilemez 4.0 Uluslararasıtr_TR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectGeneral & Internal medicineen_US
dc.subjectParkinson diseaseen_US
dc.subjectMinimal cognitive impairmenten_US
dc.subjectNeuropsychological testsen_US
dc.subjectCognitive functionsen_US
dc.subjectHippocampal volumeen_US
dc.subjectProgressive supranuclear palsyen_US
dc.subjectAlzheimers-diseaseen_US
dc.subjectLewy bodiesen_US
dc.subjectBrain atrophyen_US
dc.subjectCerebral atrophyen_US
dc.subjectDementiaen_US
dc.subjectMRIen_US
dc.subjectDeclineen_US
dc.subjectRatesen_US
dc.subjectConversionen_US
dc.subject.meshAgeden_US
dc.subject.meshAtrophyen_US
dc.subject.meshCase-control studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHippocampusen_US
dc.subject.meshHumansen_US
dc.subject.meshMagnetic resonance imagingen_US
dc.subject.meshMaleen_US
dc.subject.meshMemoryen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshMild cognitive impairmenten_US
dc.subject.meshNeuropsychological testsen_US
dc.subject.meshParkinson diseaseen_US
dc.titleImpaired cognitive performance and hippocampal atrophy in Parkinson diseaseen_US
dc.typeArticleen_US
dc.identifier.wos000362526300029tr_TR
dc.identifier.scopus2-s2.0-84943271722tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Nöroloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-2274-3230tr_TR
dc.contributor.orcid0000-0002-3425-0740tr_TR
dc.contributor.orcid0000-0001-5229-0001tr_TR
dc.identifier.startpage1173tr_TR
dc.identifier.endpage1177tr_TR
dc.identifier.volume45tr_TR
dc.identifier.issue5, Special Issueen_US
dc.relation.journalTurkish Journal of Medical Sciencesen_US
dc.contributor.buuauthorErer, Sevda-
dc.contributor.buuauthorZarifoglu, Mehmet-
dc.contributor.buuauthorHakyemez, Bahattin-
dc.contributor.buuauthorBakar, Mustafa-
dc.contributor.buuauthorKarlı, Necdet-
dc.contributor.buuauthorVarlıbaş, Zeynep Nigar-
dc.contributor.researcheridDVY-9744-2022tr_TR
dc.contributor.researcheridEHN-5825-2022tr_TR
dc.contributor.researcheridAAI-2318-2021tr_TR
dc.contributor.researcheridEKN-8251-2022tr_TR
dc.contributor.researcheridJDE-9380-2023tr_TR
dc.contributor.researcheridEDI-1148-2022tr_TR
dc.relation.collaborationYurt içitr_TR
dc.relation.collaborationSanayitr_TR
dc.indexed.trdizinTrDizintr_TR
dc.identifier.pubmed26738364tr_TR
dc.subject.wosMedicine, General & Internalen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubMeden_US
dc.wos.quartileQ4en_US
dc.contributor.scopusid25635370800tr_TR
dc.contributor.scopusid6603411305tr_TR
dc.contributor.scopusid6602527239tr_TR
dc.contributor.scopusid26643051200tr_TR
dc.contributor.scopusid6506587942tr_TR
dc.contributor.scopusid36515788700tr_TR
dc.subject.scopusParkinson's disease; Cognition; Cognitive dysfunctionen_US
dc.subject.emtreeActivity of daily living assessmenten_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeAmnesiaen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeAttention testen_US
dc.subject.emtreeBrain atrophyen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeCognition assessmenten_US
dc.subject.emtreeCognitive defecten_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeFigural fluency testen_US
dc.subject.emtreeHippocampal atrophyen_US
dc.subject.emtreeHippocampal volumeen_US
dc.subject.emtreeHippocampusen_US
dc.subject.emtreeHoehn and Yahr scaleen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeMiddle ageden_US
dc.subject.emtreeMild cognitive impairmenten_US
dc.subject.emtreeMini Mental State Examinationen_US
dc.subject.emtreeMorphometricsen_US
dc.subject.emtreeNervous system parametersen_US
dc.subject.emtreeNeuropsychological testen_US
dc.subject.emtreeNuclear magnetic resonance imagingen_US
dc.subject.emtreeParkinson diseaseen_US
dc.subject.emtreeStroop testen_US
dc.subject.emtreeTremoren_US
dc.subject.emtreeUnified Parkinson Disease Rating Scaleen_US
dc.subject.emtreeWechsler memory scaleen_US
dc.subject.emtreeAtrophyen_US
dc.subject.emtreeCase control studyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMemoryen_US
dc.subject.emtreeParkinson diseaseen_US
dc.subject.emtreePathologyen_US
dc.subject.emtreePsychologyen_US
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