Bu öğeden alıntı yapmak, öğeye bağlanmak için bu tanımlayıcıyı kullanınız:
http://hdl.handle.net/11452/34238
Başlık: | Impaired cognitive performance and hippocampal atrophy in Parkinson disease |
Yazarlar: | Yıldız, Demet Tufan, Fatih Uludağ Üniversitesi/Tıp Fakültesi/Nöroloji Anabilim Dalı. Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı. 0000-0002-2274-3230 0000-0002-3425-0740 0000-0001-5229-0001 Erer, Sevda Zarifoglu, Mehmet Hakyemez, Bahattin Bakar, Mustafa Karlı, Necdet Varlıbaş, Zeynep Nigar DVY-9744-2022 EHN-5825-2022 AAI-2318-2021 EKN-8251-2022 JDE-9380-2023 EDI-1148-2022 25635370800 6603411305 6602527239 26643051200 6506587942 36515788700 |
Anahtar kelimeler: | General & Internal medicine Parkinson disease Minimal cognitive impairment Neuropsychological tests Cognitive functions Hippocampal volume Progressive supranuclear palsy Alzheimers-disease Lewy bodies Brain atrophy Cerebral atrophy Dementia MRI Decline Rates Conversion |
Yayın Tarihi: | 2015 |
Yayıncı: | TÜBİTAK |
Atıf: | Yıldız, D. vd. (2015). "Impaired cognitive performance and hippocampal atrophy in Parkinson disease". Turkish Journal of Medical Sciences, 45(5), Special Issue, 1173-1177. |
Özet: | Background/aim: Dementia is common in Parkinson disease (PD). Since magnetic resonance imaging has been used, hippocampal atrophy has been shown in PD patients with or without dementia. In this study we sought the correlation of cognitive decline with bilateral hippocampal volume in PD patients. Materials and methods: Thirty-three patients with diagnosis of idiopathic PD and 16 healthy subjects were included in this study. PD patients were divided into two groups as normal cognitive function and mild cognitive impairment (MCI). The Mini-Mental State Examination and detailed cognitive assessment tests were performed for all patients for cognitive analyses. Depression was excluded by the Geriatric Depression Scale. Results: The mean onset age of disease was 55 years for PD patients without dementia and 59 for PD patients with MCI. According to the Hoehn-Yahr scales, 24% of patients had grade 1, 58% had grade 2, and 18% had grade 3 disease. Right and left hippocampal volumes decreased along with cognitive test scores in PD patients. Increased right hippocampal volume was correlated with forward number test in the MCI-PD group. Conclusion: These findings suggest that memory deficit is associated with hippocampal atrophy in PD patients. |
URI: | https://doi.org/10.3906/sag-1408-68 https://journals.tubitak.gov.tr/medical/vol45/iss5/28/ http://hdl.handle.net/11452/34238 |
ISSN: | 1300-0144 |
Koleksiyonlarda Görünür: | Scopus TrDizin Web of Science |
Bu öğenin dosyaları:
Dosya | Açıklama | Boyut | Biçim | |
---|---|---|---|---|
Erer_vd_2015.pdf | 147.13 kB | Adobe PDF | ![]() Göster/Aç |
Bu öğe kapsamında lisanslı Creative Commons License