Bu öğeden alıntı yapmak, öğeye bağlanmak için bu tanımlayıcıyı kullanınız: http://hdl.handle.net/11452/28977
Başlık: The peri-microvascular edema in hippocampal CA1 area in a rat model of sepsis
Yazarlar: Uludağ Üniversitesi/Tıp Fakültesi/Anatomi Bölümü.
0000-0003-3368-8123
Kafa, İlker Mustafa
Arı, İlknur
Kurt, Mustafa Ayberk
AAG-7125-2021
AAR-4341-2020
8450193200
8450193100
35603735000
Anahtar kelimeler: Septic encephalopathy
CA1
Fecal peritonitis
Hippocampus
Peri-microvascular edema
Septic encephalopathy
Brain
Lipopolysaccharide
Pathogenesis
Inflammation
Activation
Responses
Yayın Tarihi: Tem-2007
Yayıncı: Wiley
Atıf: Kafa, İ. M. vd. (2007). "The peri-microvascular edema in hippocampal CA1 area in a rat model of sepsis". Neuropathology, 27(3), 213-220.
Özet: Encephalopathy is a common complication of sepsis. However, little is known about the morphological changes that occur in the brain during sepsis. In this study, fecal peritonitis was induced in Wistar rats, which had been monitored for 4 h before their brains were removed and samples from the CA1 area taken. In addition to higher blood pressure with a decreasing pattern and a significant drop in rectal temperature, an increased heart rate and marked respiratory failure were observed. The tissue was investigated and compared with corresponding hippocampal samples taken from sham-operated and not operated control groups. Significantly more peri-microvascular edema was found in the hippocampal CA1 area in the septic group. The percentages of the peri-microvascular edema were 158.57 +/- 3.6%, 122.84 +/- 1.5% and 120.24 +/- 1.9% in the fecal peritonitis group, sham-operated and not operated control groups, respectively. The results may suggest that the edema observed around the microvessels may participate in the pathogenesis of the septic encephalopathy probably by causing in the microvascular permeability characteristics.
URI: https://doi.org/10.1111/j.1440-1789.2007.00757.x
https://onlinelibrary.wiley.com/doi/10.1111/j.1440-1789.2007.00757.x
http://hdl.handle.net/11452/28977
ISSN: 1440-1789
0919-6544
Koleksiyonlarda Görünür:PubMed
Scopus
Web of Science

Bu öğenin dosyaları:
Bu öğeyle ilişkili dosya bulunmamaktadır.


DSpace'deki bütün öğeler, aksi belirtilmedikçe, tüm hakları saklı tutulmak şartıyla telif hakkı ile korunmaktadır.