Bu öğeden alıntı yapmak, öğeye bağlanmak için bu tanımlayıcıyı kullanınız: http://hdl.handle.net/11452/34139
Başlık: The effect of immunonutrition (glutamine, alanine) on fracture healing
Yazarlar: Küçükalp, Abdullah
Sönmez, Gürsel
Uludağ Üniversitesi/Tıp Fakültesi/Ortopedi ve Travmatoloji Anabilim Dalı.
Uludağ Üniversitesi/Veteriner Fakültesi/Patoloji Anabilim Dalı.
Durak, Kemal
Bayyurt, Sarp
Bilgen, Muhammed Sadık
AAP-7233-2020
6602850051
37113699300
35723877700
Anahtar kelimeler: Alanine
Immunonutrition
Antioxidant
Glutamine
Fracture healing
Amino-acids
Arginine
Sodium
Rabbits
Food science & technology
Nutrition & dietetics
Yayın Tarihi: 8-Eki-2014
Yayıncı: Swedish Nutrition Foundation-SNF
Atıf: Küçükalp, A. vd. (2014). "The effect of immunonutrition (glutamine, alanine) on fracture healing". Food and Nutrition Research, 58.
Özet: Background: There have been various studies related to fracture healing. Glutamine is an amino acid with an important role in many cell and organ functions. This study aimed to make a clinical, radiological, and histopathological evaluation of the effects of glutamine on fracture healing. Methods: Twenty rabbits were randomly allocated into two groups of control and immunonutrition. A fracture of the fibula was made to the right hind leg. All rabbits received standard food and water. From post-operative first day for 30 days, the study group received an additional 2 ml/kg/day 20% L-alanine L-glutamine solution via a gastric catheter, and the control group received 2 ml/kg/day isotonic via gastric catheter. At the end of 30 days, the rabbits were sacrificed and the fractures were examined clinically, radiologically, and histopathologically in respect to the degree of union. Results: Radiological evaluation of the control group determined a mean score of 2.5 according to the orthopaedists and 2.65 according to the radiologists. In the clinical evaluation, the mean score was 1.875 for the control group and 2.0 for the study group. Histopathological evaluation determined a mean score of 8.5 for the control group and 9.0 for the study group. Conclusion: One month after orally administered glutamine-alanine, positive effects were observed on fracture healing radiologically, clinically, and histopathologically, although no statistically significant difference was determined.
URI: https://doi.org/10.3402/fnr.v58.24998
https://foodandnutritionresearch.net/index.php/fnr/article/view/656
http://hdl.handle.net/11452/34139
ISSN: 1654-6628
1654-661X
Koleksiyonlarda Görünür:Scopus
Web of Science

Bu öğenin dosyaları:
Dosya Açıklama BoyutBiçim 
Durak_vd_2014.pdf1.15 MBAdobe PDFKüçük resim
Göster/Aç


Bu öğe kapsamında lisanslı Creative Commons License Creative Commons